「APAGARD PREMIO」

APAGARD uses nanotechnology,
It is the pioneer of nanomedicine hydroxyapatite toothpaste.
It can effectively repair enamel, prevent dental caries, whiten teeth, and comprehensively protect oral health.

APAGARD is Japan's No. 1 selling high-function whitening toothpaste※ .

☆@COSME Best Cosmetics Award 2017 Hall of Honor Award​
☆@COSME Best Cosmetics Award 2016 Best Oral Care No. 1
☆@COSME Best Cosmetics Award 2015 Best Oral Care No. 1

■Extreme type■Contains 1.4 times of M plus and SMOKIN' medicinal hydroxyfoutite, which has better whitening and anti-caries effects ■Contains pearl whitening ingredient - hydrolyzed pearl protein liquid ■Contains xylitol ■Fluoride-free ■No abrasion Element

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Contains a high amount of medicinal hydroxyapatite.
Recommended for those who want to whiten their teeth.
Active ingredient medicinal hydroxyapatite developed by Sangi is highly compounded.
Medicated hydroxyapatite adsorbs and removes dental plaque, repairs (recrystallizes) invisible microscopic scratches on the enamel on the tooth surface.
Replenishes (regenerates) minerals to mineral-deficient areas of teeth (initial caries).
Prevents cavities with 3 actions of calcification.
A brightening prescription that combines medicinal hydroxyapatite and natural pearl ingredients (brightening agent: hydrolyzed conchiolin solution) extracted from pearls and pearl oysters.
By keeping your teeth healthy, you can bring out the whiteness and beauty of your teeth.
Refreshing light mint flavor with a gentle sweetness.
How to use:

Apply an appropriate amount (about 1 cm) to the toothbrush and brush well so that the medicinal ingredients work.
Especially before going to bed, brush carefully.